Washington University Researchers Develop Personalized Vaccine for Brain Cancer Patients

St. Louis, Mo. (KFMO) - Scientists at Washington University School of Medicine are developing a personalized vaccine designed to help extend the lives of patients battling aggressive forms of brain cancer.

Researchers say the experimental treatment is tailored for each individual patient by using samples taken directly from their tumor. The vaccine is designed to help the immune system recognize and attack cancer cells more effectively.

Neurosurgeon-scientist Dr. Albert Kim says research involving glioblastoma, one of the deadliest forms of brain cancer, is reaching what he describes as an “inflection point” as scientists continue making advancements in treatment options.

In a phase one clinical trial, researchers found the vaccine was safe for patients and helped prolong overall survival. The early-stage study focused on evaluating both safety and effectiveness in patients diagnosed with glioblastoma.

The research was led by Washington University School of Medicine and the findings were published in the journal Nature Cancer.

Researchers say additional studies and larger clinical trials will be needed before the treatment could become widely available to patients.