Blue Division Standings
| Record | GB | Home | Road | Streak | |
| ◈ - Festus | 10-3 | -- | 6-2 | 4-1 | Lost 1 |
| North County | 6-6 | 3.5 | 1-3 | 5-3 | Lost 1 |
| DeSoto | 5-5 | 3.5 | 1-4 | 4-1 | Lost 1 |
| Hillsboro | 5-6 | 4.0 | 2-3 | 3-3 | Lost 1 |
| Windsor | 4-6 | 4.5 | 3-2 | 1-4 | Lost 1 |
◈ - Won District Title
White Division Standings
| Record | GB | Home | Road | Streak | |
| Valle Catholic | 10-1 | -- | 6-1 | 4-0 | Lost 1 |
| Ste. Genevieve | 9-2 | 1.0 | 5-1 | 4-1 | Lost 1 |
| Potosi | 7-5 | 3.5 | 2-2 | 5-3 | Lost 1 |
| Central | 6-5 | 5.0 | 4-3 | 3-2 | Lost 1 |
| Fredericktown | 2-8 | 7.5 | 2-3 | 0-5 | Lost 1 |
◈ - Won District Title
Other Area Teams
| Record | Home | Road | Streak | |
| ◈ - Farmington | 9-3 | 6-2 | 3-1 | Lost 1 |
◈ - Won District Title
Central Rebels Football
Head Coach: Kory Schweiss • 22nd year| 8/29/2025 | Owensville | @ | Central | W 37-0 |
| 9/5/2025 | Central | @ | Jefferson | W 21-20 (OT) |
| 9/12/2025 | Fredericktown | @ | Central | W 43-0 |
| 9/19/2025 | St. Dominic | @ | Central | L 42-21 |
| 9/26/2025 | Central | @ | Ste. Genevieve | L 35-7 |
| 10/3/2025 | Central | @ | Potosi | W 31-28 |
| 10/10/2025 | Valle Catholic | @ | Central | L 40-20 |
| 10/17/2025 | Dexter | @ | Central | W 22-21 |
| 10/24/2025 | Central | @ | Farmington | L 56-12 |
| 10/30/2025 | Class 3, District 1 Tournament | |||
| 10/30/2025 | 2-Central vs 7-Fredericktown | W 37-22 | ||
| 11/7/2025 | 2-Central vs 3-Potosi | L 35-28 | ||
DeSoto Dragons Football
Head Coach: Russ Schmidt • 3rd year| 8/29/2025 | DeSoto | @ | Freeburg, IL | L 30-14 |
| 9/5/2025 | DeSoto | @ | Perryville | W 31-14 |
| 9/12/2025 | North County | @ | DeSoto | L 14-13 |
| 9/19/2025 | Festus | @ | DeSoto | L 33-0 |
| 9/26/2025 | DeSoto | @ | Windsor | W 41-14 |
| 10/3/2025 | Fredericktown | @ | DeSoto | W 36-7 |
| 10/10/2025 | DeSoto | @ | Hillsboro | W 26-20 |
| 10/17/2025 | Potosi | @ | DeSoto | L 40-14 |
| 10/24/2025 | DeSoto | @ | Herculaneum | W 35-26 |
| 10/31/2025 | Class 4, District 1 Tournament | |||
| 10/31/2025 | 3-DeSoto vs 6-North County | L 21-6 | ||
Farmington Knights Football
Head Coach: Brent Eckley • 1st year| 8/29/2025 | North County | @ | Farmington | W 49-16 |
| 9/5/2025 | Farmington | @ | St. Clair | W 60-27 |
| 9/12/2025 | Poplar Bluff | @ | Farmington | W 49-13 |
| 9/19/2025 | Jackson | @ | Farmington | L 56-7 |
| 9/26/2025 | Farmington | @ | Sikeston | W 42-6 |
| 10/3/2025 | Union | @ | Farmington | W 49-14 |
| 10/10/2025 | Farmington | @ | Cape Central | W 35-21 |
| 10/17/2025 | Farmington | @ | Festus | L 41-36 |
| 10/24/2025 | Central | @ | Farmington | W 56-12 |
| 10/30/2025 | Class 5, District 1 Tournament | |||
| 11/7/2025 | 1-Farmington vs 4-Fox | W 49-28 | ||
| 11/14/2025 | 1-Farmington vs 2-Cape Central | W 21-0 | ||
| 11/22/2025 | Class 5 State Tournament | |||
| 11/22/2025 | Farmington vs Kirkwood | L 70-56 | ||
Festus Tigers Football
Head Coach: AJ Ofodile • 6th year| 8/29/2025 | Festus | @ | Rolla | W 30-14 |
| 9/5/2025 | Francis Howell Central | @ | Festus | W 35-7 |
| 9/12/2025 | Windsor | @ | Festus | W 56-14 |
| 9/19/2025 | Festus | @ | DeSoto | W 33-0 |
| 9/26/2025 | Hillsboro | @ | Festus | W 40-14 |
| 10/3/2025 | Festus | @ | North County | W 46-21 |
| 10/10/2025 | Festus | @ | DeSmet Jesuit | L 56-28 |
| 10/17/2025 | Farmington | @ | Festus | W 41-36 |
| 10/24/2025 | Jackson | @ | Festus | L 62-21 |
| 10/31/2025 | Class 4, District 1 Tournament | |||
| 11/7/2025 | 1-Festus vs 4-Hillsboro | W 41-0 | ||
| 11/14/2025 | 1-Festus vs 6-North County | W 42-24 | ||
| 11/22/2025 | Class 4 State Tournament | |||
| 11/22/2025 | Festus vs Sullivan | W 42-7 | ||
| 11/29/2025 | Festus vs Kearney | L 52-24 | ||
Fredericktown Blackcats Football
Head Coach: Steve Williams • 3rd year| 8/29/2025 | Perryville | @ | Fredericktown | L 35-21 |
| 9/5/2025 | Fredericktown | @ | Herculaneum | L 28-0 |
| 9/12/2025 | Fredericktown | @ | Central | L 43-0 |
| 9/19/2025 | Fredericktown | @ | Valle Catholic | L 57-0 |
| 9/26/2025 | Potosi | @ | Fredericktown | L 48-15 |
| 10/3/2025 | Fredericktown | @ | DeSoto | L 36-7 |
| 10/10/2025 | Ste. Genevieve | @ | Fredericktown | L 56-13 |
| 10/17/2025 | Windsor | @ | Fredericktown | W 39-22 |
| 10/24/2025 | East Prairie | @ | Fredericktown | W 40-14 |
| 10/30/2025 | Class 3, District 1 Tournament | |||
| 10/30/2025 | 2-Central vs 7-Fredericktown | L 37-22 | ||
Hillsboro Hawks Football
Head Coach: Bill Sucharski • 6th year| 8/29/2025 | Hillsboro | @ | Moberly | W 44-34 |
| 9/5/2025 | SLUH | @ | Hillsboro | L 35-14 |
| 9/12/2025 | Hillsboro | @ | Washington | W 27-16 |
| 9/19/2025 | Hillsboro | @ | North County | W 28-6 |
| 9/26/2025 | Hillsboro | @ | Festus | L 40-14 |
| 10/3/2025 | Windsor | @ | Hillsboro | W 41-12 |
| 10/10/2025 | DeSoto | @ | Hillsboro | L 26-20 |
| 10/17/2025 | Chaminade | @ | Hillsboro | L 42-7 |
| 10/24/2025 | Hillsboro | @ | Poplar Bluff | L 30-21 |
| 10/31/2025 | Class 4, District 1 Tournament | |||
| 10/31/2025 | 4-Hillsboro vs 5-Sikeston | W 35-21 | ||
| 11/7/2025 | 1-Festus vs 4-Hillsboro | L 41-0 | ||
North County Raiders Football
Head Coach: Brian Jones • 9th year| 8/29/2025 | North County | @ | Farmington | L 49-16 |
| 9/5/2025 | North County | @ | Glenwood, IL | L 48-0 |
| 9/12/2025 | North County | @ | DeSoto | W 14-13 |
| 9/19/2025 | Hillsboro | @ | North County | L 28-6 |
| 9/26/2025 | Rolla | @ | North County | L 42-14 |
| 10/3/2025 | Festus | @ | North County | L 46-21 |
| 10/10/2025 | North County | @ | Windsor | W 36-0 |
| 10/16/2025 | North County | @ | St. Clair | W 24-14 |
| 10/23/2025 | Sullivan | @ | North County | W 24-22 |
| 10/31/2025 | Class 4, District 1 Tournament | |||
| 10/31/2025 | 3-DeSoto vs 6-North County | W 21-6 | ||
| 11/7/2025 | 2-Perryville vs 6-North County | W 51-7 | ||
| 11/14/2025 | 1-Festus vs 6-North County | L 42-24 | ||
Potosi Trojans Football
Head Coach: Mark Casey • 1st year| 8/29/2025 | Potosi | @ | St. Clair | L 35-21 |
| 9/5/2025 | Potosi | @ | Charleston | W 39-8 |
| 9/12/2025 | Potosi | @ | Valle Catholic | L 47-15 |
| 9/19/2025 | Ste. Genevieve | @ | Potosi | L 25-24 |
| 9/26/2025 | Potosi | @ | Fredericktown | W 48-15 |
| 10/3/2025 | Central | @ | Potosi | L 31-28 |
| 10/10/2025 | Pacific | @ | Potosi | W 27-20 |
| 10/17/2025 | Potosi | @ | DeSoto | W 40-14 |
| 10/24/2025 | Potosi | @ | St. Charles West | W 48-41 |
| 10/30/2025 | Class 3, District 1 Tournament | |||
| 10/31/2025 | 3-Potosi vs 6-Doniphan | W 63-31 | ||
| 11/7/2025 | 2-Central vs 3-Potosi | W 35-28 | ||
| 11/14/2025 | 1-Dexter vs 3-Potosi | L 33-12 | ||
Ste. Genevieve Dragons Football
Head Coach: Jay Pope • 5th year| 8/29/2025 | St. Vincent | @ | Ste. Genevieve | W 49-35 |
| 9/5/2025 | Ste. Genevieve | @ | University City | W 27-13 |
| 9/12/2025 | Ste. Genevieve | @ | Kennett | W 29-15 |
| 9/19/2025 | Ste. Genevieve | @ | Potosi | W 25-24 |
| 9/26/2025 | Central | @ | Ste. Genevieve | W 35-7 |
| 10/3/2025 | Valle Catholic | @ | Ste. Genevieve | L 31-13 |
| 10/10/2025 | Ste. Genevieve | @ | Fredericktown | W 56-13 |
| 10/17/2025 | Jefferson | @ | Ste. Genevieve | W 55-14 |
| 10/24/2025 | Caruthersville | @ | Ste. Genevieve | W 30-9 |
| 10/31/2025 | Class 3, District 2 Tournament | |||
| 10/31/2025 | 3-Ste. Genevieve vs 6-Normandy | W 13-0 (Forfeit) | ||
| 11/7/2025 | 2-Lift for Life vs 3-Ste. Genevieve | L 48-41 | ||
Valle Catholic Warriors Football
Head Coach: Judd Naeger • 21st year| 8/29/2025 | Monroe City | @ | Valle Catholic | W 41-22 |
| 9/5/2025 | Valle Catholic | @ | St. Vincent | W 42-7 |
| 9/12/2025 | Potosi | @ | Valle Catholic | W 47-15 |
| 9/19/2025 | Fredericktown | @ | Valle Catholic | W 57-0 |
| 9/26/2025 | Valle Catholic | @ | Caruthersville | W 23-13 |
| 10/3/2025 | Valle Catholic | @ | Ste. Genevieve | W 31-13 |
| 10/10/2025 | Valle Catholic | @ | Central | W 40-20 |
| 10/17/2025 | Bowling Green | @ | Valle Catholic | W 56-6 |
| 10/24/2025 | St. Pius | @ | Valle Catholic | W 14-7 |
| 10/31/2025 | Class 3, District 2 Tournament | |||
| 11/7/2025 | 1-Valle Catholic vs 4-Herculaneum | W 49-8 | ||
| 11/14/2025 | 1-Valle Catholic vs 2-Lift for Life | L 48-34 | ||
Windsor Owls Football
Head Coach: Lee Freeman • 2nd year| 8/29/2025 | Herculaneum | @ | Windsor | W 36-28 (2OT) |
| 9/5/2025 | Affton | @ | Windsor | W 36-6 |
| 9/12/2025 | Windsor | @ | Festus | L 56-14 |
| 9/19/2025 | Windsor | @ | Clayton | W 66-26 |
| 9/26/2025 | DeSoto | @ | Windsor | L 41-14 |
| 10/3/2025 | Windsor | @ | Hillsboro | L 41-12 |
| 10/10/2025 | North County | @ | Windsor | L 36-0 |
| 10/17/2025 | Windsor | @ | Fredericktown | L 39-22 |
| 10/24/2025 | Bayless | @ | Windsor | W 46-6 |
| 10/31/2025 | Class 4, District 1 Tournament | |||
| 10/31/2025 | 2-Perryville vs 7-Windsor | L 39-14 | ||